Aristotle , in the 4th century B.C., promoted the idea that the embryo develops from a formless mass that resulted from the union of semen with menstrual blood. Aristotle believed that the male was the major factor in reproduction, although he did grant that the female supplied the matter for shaping. Galen , 2nd century A.D., wrote a book entitled “ On the formation of the foetus”, also held the two-seed doctrine, claiming both the male and female seeds had coagulative power and receptive capacity for coagulation but that one was stronger in the male and the other in the female.From the time of Galen , until the 16th century, the prevailed wrong misconception that the embryo will grow in the uterus containing clotted menstrual blood as a seed till complete growth, with no record of major advances in the field of embryology.
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